Please use this identifier to cite or link to this item: http://archive.cmb.ac.lk:8080/xmlui/handle/70130/6577
Title: Low-cost microfluidic electrochemical paper-based device to detect glucose
Authors: Kaumal, M. N.
Jayarathna, H. K. V. S.
Fernando, W. T. H.
Keywords: non-invasive
Low-cost µPAD
Diabetic monitoring
Non-enzymatic
Environmental friendly
Issue Date: 2022
Publisher: University of Kelaniya Sri Lanka
Citation: Fernando, W.T.H., Jayarathna, H.K.V.S. and Kaumal, M.N., 2022. Low-cost microfluidic electrochemical paper-based device to detect glucose. Journal of Science of the University of Kelaniya Sri Lanka, 15(1), pp.21–33. DOI: http://doi.org/10.4038/josuk.v15i1.8043
Abstract: Continuous monitoring of the level of glucose is essential to maintain the health of a diabetic patient. The use of invasive methods to obtain blood samples to detect glucose is the current method, but such methods may not be preferred by patients. Non-invasive methods such as the determination of glucose based on saliva or sweat can be preferred by patients for continuous monitoring. A low-cost electrochemical microfluidic paper-based analytical device (µPAD) suitable to monitor glucose levels using sweat and saliva is introduced. This device is extremely low-cost due to the use of a paper matrix and varnish for the fabrication of paper. Pseudo-reference stainless steel is used with a working electrode anodized using sodium potassium tartrate tetrahydrate for the development of a three-electrode system. Cyclic voltammetric-based analysis of glucose with µPAD produced a linear response in the working range of 1-10 mmol dm^-3 with a limit of detection of 0.058 mol dm^-3. The detection of diabetic conditions using saliva and sweat is possible using the device by correlating to the blood glucose levels using prior literature data.
URI: http://archive.cmb.ac.lk:8080/xmlui/handle/70130/6577
ISSN: 2513-2180
Appears in Collections:Department of Chemistry

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