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DC Field | Value | Language |
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dc.contributor.author | Gunawardane, P.T.K. | - |
dc.contributor.author | Wijeyaratne, C.N. | - |
dc.contributor.author | Arandara, D.C. | - |
dc.contributor.author | Arasalingam, A. | - |
dc.contributor.author | Dodampahala, S.H. | - |
dc.contributor.author | Seneviratne, H.R. | - |
dc.date.accessioned | 2021-09-29T07:17:26Z | - |
dc.date.available | 2021-09-29T07:17:26Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | Gunawardane, P. T. K., Wijeyaratne, C. N., Arandara, D. C., Arasalingam, A., Dodampahala, S. H., & Seneviratne, H. R. (2006). Gestational diabetes mellitus (GDM): risk factors and impact on neonatal outcome of an indigenous South Asian cohort. | en_US |
dc.identifier.uri | http://archive.cmb.ac.lk:8080/xmlui/handle/70130/6156 | - |
dc.description.abstract | OBJECTIVE: To assess risk factors and pregnancy outcomes of GDM in Sri Lankans. DESIGN: Case-control study SETTING: Department of Obstetrics & Gynaecology, Faculty of Medicine University of Colombo, Sri Lanka. SAMPLE: 274 indigenous Sri Lankans with previous GDM and 168 ethnically matched controls. METHODS: Post partum review of hospital case records and by patient interview, of risk factors and outcome of index pregnancy managed in a single unit (ACOG guidelines, 2001). RESULTS (GDM VS. CONTROLS): Risk factors - Mean age 33.4ñ0.6 vs. 32.3ñ0.8 years. 78 percent GDM para2 or > with 33.7 percent having 2 or > children vs. 74 percent controls para 2 or > with 60 percent having 2 or > children (p = 0.001). Significant risks included maternal age >35 years (OR=1.8, 95 percent CI=1.1-2.8, p=0.008), previous stillbirth with fetal macrosomia (OR=3.55,95 percent CI= 1.6-8.2, p=0.005), family history of diabetes (OR=4.5, 95 percent CI=1.6-6.9, p=0.004), and high maternal BMI at antenatal booking (OR=16.8, 95 percent CI= 9.6-26.9, p=0.00001). 39 (14.2 percent) in GDM group had previous GDM. OUTCOME OF INDEX PREGNANCY MANAGED FOR GDM VS. CONTROLS: Mean period of gestation at delivery 3 8.1 ñ1.9 vs. 38.2ñ2.05 weeks, p>0.05.Pre-term delivery 34(12.4 percent) vs. 19(5.3 percent), p=0.01. Vaginal delivery 110(40.1 percent) vs. 95(56.5 percent), p=0.08, Caesarean delivery 164(59.8 percent) vs. 73(43.4 percent), p= 0.01. Live births 270(98.5 percent) vs. 168(100 percent), p=0.1, stillbirth 4(1.5 percent) vs. 0, p=0.001. Mean birth weight (BW) 3.01ñ0.56 vs. 3.03ñ0.54kg, p=0.08; Low BW 42(15.3 percent) vs. 19(11.3 percent), p=0.1 and BW >3.5kg (2SDS) 42(15.3 percent) vs. 16(9.5 percent), p=0.1. CONCLUSIONS: Sri Lankan women have similar risks for developing GDM as reported in other ethnic groups, with maternal obesity a leading contributor. This data confirms early detection and effective control of gestational diabetes leads to significant reduction of perinatal morbidity and mortality. | en_US |
dc.language.iso | en | en_US |
dc.publisher | The Sri Lanka College of Obstetricians and Gynaecologists | en_US |
dc.subject | GDM | en_US |
dc.subject | ASIAN | en_US |
dc.title | Gestational diabetes mellitus (GDM): risk factors and impact on neonatal outcome of an indigenous South Asian cohort | en_US |
dc.type | Article | en_US |
Appears in Collections: | Articles (local / International) |
Files in This Item:
File | Description | Size | Format | |
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Gestational diabetes mellitus (GDM).doc | 39 kB | Microsoft Word | View/Open |
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