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http://archive.cmb.ac.lk:8080/xmlui/handle/70130/5770
Title: | Hyperhaemolysis syndrome in haemoglobin E / beta thalassaemia responding to cyclophosphamide therapy |
Authors: | Senanayake, M. P. Kuruppu, K. K. S. Sumanasena, S. P. Lamabadusuriya, S. P. |
Keywords: | Hyperhaemolysis syndrome Thalassaemia cyclophosphamide therapy |
Issue Date: | 2008 |
Publisher: | Sri Lanka Medical Association |
Citation: | Senanayake, M. P., Kuruppu, K. K. S., Sumanasena, S. P., & Lamabadusuriya, S. P. (2012). Hyperhaemolysis syndrome in haemoglobin E/beta thalassaemia responding to cyclophosphamide therapy. |
Abstract: | Hyperhaemolysis syndrome (HS) is a rare condition where blood transfusions are followed by destruction of both donor and recipient red cells, in the absence of significant detectable red cell antibodies. This phenomenon is reported only in a few children and is extremely rare in thalassaemia syndromes. We report a case of HS in a child with low G6PD enzyme levels and Hb E beta thalassaemia, in whom intravenous immunoglobulin (IVIG), oral methylprednisolone and splenectomy failed but cyclophosphamide therapy resulted in a successful outcome. |
URI: | http://archive.cmb.ac.lk:8080/xmlui/handle/70130/5770 |
Appears in Collections: | Articles (local / International) |
Files in This Item:
File | Description | Size | Format | |
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hyperhaemo.pdf | 79.91 kB | Adobe PDF | View/Open |
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