Please use this identifier to cite or link to this item:
http://archive.cmb.ac.lk:8080/xmlui/handle/70130/1991
Title: | An investigation of in vivo antimalarial activity of black tea brew of Camellia sinensis L.O. Kuntze in mice |
Authors: | Ratnasooriya, W.D. Jayasinghe, C.D. Udagama-Randeniya, P.V. |
Issue Date: | 2007 |
Citation: | S.I.J. tea Sci. 72(I). 9-15. 2007 |
Abstract: | Sc\cral traditional medicines and folklore beliefs exist that black tea brew f RTB) frv^n Caincllia sinensis L. 0 . Kuntze: (Thcaceae) possesses antimalarial acn\\s stiuK' scienlifiealh' in\'cstigatcd the aiiliniaiaria! potential (in terms ot^nntiparastic a c n \ i i \ of C sinensis using Sn Lankan high grown Dust grade No. 1 tea in vr.-n \n m^c against Plasmodium yoelti. 1336 mg/kg of B T B 'da\[ to 24 cups) or chloroquinc or water was orally administered to three different groups (n • ^'group) of mice for 3 consecutive days and the schizonticidal activity determined. The results showed no significant (P > 0.05) schizonticidal acti\'il\ either on earh infection os the established malarial infections (measured in terms of parasitaemia. ciieniosiipprcsion and mean survn'a! time). However, the number of survi\ing mice :i! 4 post inocLikinon was higher in the BTB treated group, compared with the \ehicic. it is concluded that B T B ma\ not bo effective against F. falciparum human malaria contrar\ to the beliefs of traditional medicines and folklore tiiat it is effccti\. |
URI: | http://archive.cmb.ac.lk:8080/xmlui/handle/70130/1991 |
Appears in Collections: | Department of Zoology |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
profR005.pdf | 213.08 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.